Searchable abstracts of presentations at key conferences in endocrinology

Endocrine Abstracts

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ea0037ep661 | Pituitary: basic and neuroendocrinology | ECE2015

Long-term follow-up of cranially irradiated childhood leukaemia survivors show cognitive impairment and progressive decline in sustained attention, in spite of on complete hormone replacement

Follin Cecilia , Johansson Aki , Osterberg Kai , Rovira Andrea , Jansson Magdalena , Wiebe Thomas , Erfurth Eva Marie

Background: Survivors of childhood leukaemia (ALL) treated with cranial radiotherapy (CRT) are at risk for cognitive impairment. Whether the impairment progresses with follow-up time and if survivors with cognitive impairment have an increased risk for overweight, is unknown. We aimed to investigate the long-term cognitive functioning in ALL survivors treated with CRT in comparison to matched controls.Method: Cognitive functioning was investigated in 38 ...
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ea0037gp.18.04 | Pituitary–Basic and IGF-1 | ECE2015

A small hypothalamic volume correlates with impaired cognitive outcome in childhood onset craniopharyngioma on long-term follow up

Fjalldal Sigridur , Follin Cecilia , Gabery Sanaz , Petersen AEsa , Rylander Lars , Ekman Bertil , Johansson Aki , Osterberg Kai , Jansson Magdalena , Rovira Andrea , Erfurth Eva-Marie

Background: Hypothalamic damage caused by craniopharyngioma (CP) is related to memory deficits, disturbed attention, and impaired processing speed. This is the first study that aims to establish a structure to function relationship by assessing cognitive function in adult patients with childhood-onset (CO) CP along with volumetric analysis of the hypothalamus.Method: Forty-one (24 women) surgically treated CO-CP patients (median age at diagnosis; 11 year...
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ea0049gp182 | Pituitary | ECE2017

Brain white matter damage and volumes of hippocampus and hypothalamus correlates to cognitive function in craniopharyngioma

Fjalldal Sigridur , Svard Daniel , Follin Cecilia , Westen Danielle Van , Gabery Sanaz , Petersen AEsa , Jansson Magdalena , Sundgren Pia Maly , Bjorkman-Burtscher Isabella , Latt Jimmy , Mannfolk Peter , Nordstrom Carl-Henrik , Rylander Lars , Ekman Bertil , Johansson Aki , Erfurth Eva-Marie

Introduction: Adult patients with craniopharyngioma (CP) and hypothalamic (HT) damage have impaired cognitive function. The white matter (WM) changes behind these findings remain to be elucidated. Diffusion tensor imaging (DTI) is a MRI technique that quantifies microstructural damage in the WM. This is the first study of DTI, hippocampal (HC) and HT volume in relation to cognition in CP patients.Methods: A cross-sectional study of childhood onset CP was...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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